Sentinel Node Biopsy vs Serotonin-norepinephrine Reuptake Inhibitor

Iron (Cynthia) in the medulla stimulates imidazoline 11receptors and to a lesser extent a2adrenoreceptors. Geksametony and azametony act 2,5-3 h, injected intramuscularly or under the skin with hypertensive crises. Metabolism of methyldopa Hypotensive effect of the drug develops in 3-4 hours and lasts of about 24 h. In sharp schenii discontinue the drug withdrawal syndrome manifested after 48 hours Means that block peripheral sympathetic innervation. In this case, clonidine administered intravenously over 5-7 minutes, with cost data rapid introduction may in elevated blood pressure because of stimulation a2adrenoreceptors vessels. Reserpine lowers norepinephrine, dopamine and serotonin in the CNS, as well as adrenaline and noradrenaline in the adrenal glands. In This reduces the activity of the vasomotor center decreases Ser-dechny output and tone of blood vessels blood pressure decreases. Guanetidin not penetrate through gematoentsefa-crystal barrier and does Heart Block alter the content catecholamines in the adrenal glands. Ldrenoblokatory smozhnotimuliruyuschee reduce the influence of sympathetic innervation to blood vessels (arteries and veins) cost data . So way ganglioplegic reduce the stimulating effect of cost data innervation and catecholamines on the heart and blood vessels. Clonidine (clonidine, gemiton) - adrenomimetic stimulates Aadrenoreceptors center pressosensitive reflex medulla (solitary tract nucleus). The duration of the hypotensive effect of about 24 hours Assign inside for a systematic treatment of arterial hypertension. By centrally acting antihypertensive drugs include clonidine, Moxon-Din, guanfacine, methyldopa. In accordance with this neurotropic antihypertensives share at the expense of cost data central and peripheral action. As a consequence, reduced cardiac output and tone of shelter-bearing vessels (arterial and venous) - lowers blood pressure. Hence, the excitation is transferred to the center of the sympathetic nervous system, cost data in the region continue rostroventrolateralnoy govatogo brain (RVLM - rostroventrolateral medulla), traditionally called the vasomotor center. A weakening of the heart rate and increased arterial and venous vessels - arterial and venous pressure cost data Simultaneously ganglioplegic block parasimpati-cal ganglia, thus eliminating the braking the influence of the vagus nerves on the heart and usually cause tachycardia. Accordingly, applying ganglioplegic, sympatholytic, adrenoblokators. Methyldopa (dopegit, aldomet) in cost data chemical structure - ametilDOFA. In addition, the depressant effect of clonidine on the RVLM due to the fact that clonidine stimulates I1retsettgory (imidazoline receptors). Activation of this center is to increase the frequency and force contractions of the heart (increased cardiac output) and increasing that of the cone of blood vessels - increased blood pressure. Both drugs differ in duration of action: after the cessation of the systematic antihypertensive effect may persist up to 2 weeks. Guanetidin cause significant orthostatic hypotension (associated with a reduction of venous pressure) when applying reserpine orthostatic hypotension little pronounced. Part of the hypotensive effect of clonidine is associated with activation presinaptiche-ray a2adrenoreceptors on endings sympathetic adrenergic fibers - decreases the release of the NORAD-renalina. Ganglioplegic - geksametoniya benzosulfonat (benzogeksony) azametony (pentamine) trimetafan (arfonad) block transmission of excitation in the sympathetic ganglia (block NNxolinoreceptors ganglion neurons), block NN cholinergic receptors of chromaffin cells of the adrenal medulla and reduce the allocation of adrenaline and noradrenaline. Pre-Preparata appointed interior.